Fiche du document
- doi: 10.1186/s13014-015-0386-8
- issn: 1748-717X
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1186/s13014-015-0386-8
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/25890308
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/eissn/1748-717X
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_019C5E2C4A0D2
info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer
Sujets proches
Recording and registry acts Vital records Registration Recording and registration--Law and legislationCiter ce document
C. Boydev et al., « Development of CBCT-based prostate setup correction strategies and impact of rectal distension. », Serveur académique Lausannois, ID : 10.1186/s13014-015-0386-8
Métriques
Partage / Export
Résumé
BACKGROUND: Cone-beam computed tomography (CBCT) image-guided radiotherapy (IGRT) systems are widely used tools to verify and correct the target position before each fraction, allowing to maximize treatment accuracy and precision. In this study, we evaluate automatic three-dimensional intensity-based rigid registration (RR) methods for prostate setup correction using CBCT scans and study the impact of rectal distension on registration quality. METHODS: We retrospectively analyzed 115 CBCT scans of 10 prostate patients. CT-to-CBCT registration was performed using (a) global RR, (b) bony RR, or (c) bony RR refined by a local prostate RR using the CT clinical target volume (CTV) expanded with 1-to-20-mm varying margins. After propagation of the manual CT contours, automatic CBCT contours were generated. For evaluation, a radiation oncologist manually delineated the CTV on the CBCT scans. The propagated and manual CBCT contours were compared using the Dice similarity and a measure based on the bidirectional local distance (BLD). We also conducted a blind visual assessment of the quality of the propagated segmentations. Moreover, we automatically quantified rectal distension between the CT and CBCT scans without using the manual CBCT contours and we investigated its correlation with the registration failures. To improve the registration quality, the air in the rectum was replaced with soft tissue using a filter. The results with and without filtering were compared. RESULTS: The statistical analysis of the Dice coefficients and the BLD values resulted in highly significant differences (p