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2013
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info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0056522
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info:eu-repo/semantics/altIdentifier/pmid/23437154
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info:eu-repo/semantics/altIdentifier/pissn/1932-6203
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_3EB583569A077
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R. Faiss et al., « Significant molecular and systemic adaptations after repeated sprint training in hypoxia », Serveur académique Lausannois, ID : 10.1371/journal.pone.0056522
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While intermittent hypoxic training (IHT) has been reported to evoke cellular responses via hypoxia inducible factors (HIFs) but without substantial performance benefits in endurance athletes, we hypothesized that repeated sprint training in hypoxia could enhance repeated sprint ability (RSA) performed in normoxia via improved glycolysis and O(2) utilization. 40 trained subjects completed 8 cycling repeated sprint sessions in hypoxia (RSH, 3000 m) or normoxia (RSN, 485 m). Before (Pre-) and after (Post-) training, muscular levels of selected mRNAs were analyzed from resting muscle biopsies and RSA tested until exhaustion (10-s sprint, work-to-rest ratio 1ratio2) with muscle perfusion assessed by near-infrared spectroscopy. From Pre- to Post-, the average power output of all sprints in RSA was increased (p