Study of Dementia in Swedish Twins, 1990-1999

Résumé 0

The Study of Dementia in Swedish Twins was designed to study the relative influence of genetic and environmental factors for Alzheimer's disease and other types of dementia and to test the role of specific environmental exposures that might constitute risk or protective factors for dementia. The first seven years of the Study of Dementia in Swedish Twins was based on the population from the SWEDISH ADOPTION/TWIN STUDY OF AGING (SATSA), 1984, 1987, 1990, and 1993 (ICPSR 3843). SATSA consists of a subset of 3,838 same-sex twins from the population-based Swedish Twin Registry; however, the baseline sample for the Study of Dementia in Swedish Twins consists of 2,394 individuals who were alive and born in 1935 or earlier. The Study of Dementia in Swedish Twins data cover background information (sex, zygosity, rearing status, ages at each data collection point, age at death), cognitive screening (which took place in conjunction with each SATSA wave of data collection), clinical dementia diagnoses for those who received a complete dementia workup (both baseline and longitudinal), cognitive test results (both baseline and longitudinal), medical history and medical risk factors (medical examination; blood pressure; laboratory results; history of neurologic, coronary, mental, and other diseases; smell test; history of head injury, anaesthesia, fevers, medications, dietary history with respect to fish, raw meat, and acidic foods prepared in aluminum pans), residential, occupational, and leisure activities history (including exposure related to welding, hairdressing, agriculture, medical settings, painting and other sources of organic solvents, crystal, carbon monoxide, radiation, raw meat and game; participation in contact sports; antiperspirant containing aluminum; history of smoking; history of use of alcohol), family history of dementia, and APOE genotype. SATSA is archived separately at ICPSR, see ICPSR 3843. The SATSA and the Study of Dementia in Swedish Twins files contain a common ID number that can be used to create a crosswalk between the files.