National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use]

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30 juin 2014

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Kathleen Mullan Harris et al., « National Longitudinal Study of Adolescent Health (Add Health), 1994-2008: DNA [Restricted Use] », Inter-university Consortium for Political and Social Research, ID : 10.3886/ICPSR27031.v5


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The National Longitudinal Study of Adolescent Health (Add Health) is a longitudinal study of a nationally representative sample of adolescents in grades 7-12 in the United States during the 1994-1995 school year. The Add Health cohort has been followed into young adulthood with four in-home interviews, the most recent in 2008, when the sample was aged 24-32. Add Health combines longitudinal survey data on respondents' social, economic, psychological, and physical well-being with contextual data on the family, neighborhood, community, school, friendships, peer groups, and romantic relationships, providing unique opportunities to study how social environments and behaviors in adolescence are linked to health and achievement outcomes in young adulthood. The fourth wave of interviews expanded the collection of biological data in Add Health to understand the social, behavioral, and biological linkages in health trajectories as the Add Health cohort ages through adulthood. This component of the Add Health restricted data is the Wave III DNA Data File. The DNA data contain full sibling and twin DNA results. Twin and full siblings interviewed at Wave III were asked to provide saliva samples for DNA analysis. This dataset contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine receptor), SLC6A4 (serotonin transporter), MAOA-u (monoamine oxidase A- uVNTR), DRD2 (dopamine D2 receptor), and CYP2A6 (cytochromeP450 2A6) from these samples. The Wave IV DNA Data file contains the genotype values for DAT1 (dopamine transporter), DRD4 (dopamine D4 receptor), HTTLPR (serotonin transporter), MAOA-u (monoamine oxidase A-uVNTR), LaLgS, TRI (triallelic activity bins in 5HTTLPR), DRD2 (dopamine D2 receptor), RS4680, RS12945042, DRD5 (dopamine D5 receptor), MAOCA1 (monoamine oxidase a dinucleotide). For more information, please see the study website.

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