Pharmacogénomique et aide à la prescription médicamenteuse [Pharmacogenomics : a toolbox to improve drug prescription]
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25 novembre 2020
- doi: 10.53738/REVMED.2020.16.716.2259
- issn: 1660-9379
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info:eu-repo/semantics/altIdentifier/pmid/33237643
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_227B3780CEBD4
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Genomes--Effect of drugs on Pharmacology--Genetic aspects Cambistry International exchange Exchange, Foreign Foreign exchange problem Foreign currency Currency exchange FX (Finance) Foreign money Forex Demography Demographics Farmacogenética Ensayos de propiedades mecánicas Cambio extranjero Cambio internacional Cambio monetario Divisas Mercado de divisas Moneda--Cambio exterior Médicaments thiopuriniques RN 136470-78-5 Pharmacogénomique RN 446-86-6 Possibilité (logique) Possible Impossible Possibilité (philosophie) Impossibilité Épreuves de tests Natalité Dimension de la population Surpeuplement Surpopulation Accroissement de population Devises (monnaie) Cambisme Importations de capitaux Change international Change étranger Exportations de capitauxCiter ce document
E. Jaccard et al., « Pharmacogénomique et aide à la prescription médicamenteuse [Pharmacogenomics : a toolbox to improve drug prescription] », Serveur académique Lausannois, ID : 10.53738/REVMED.2020.16.716.2259
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Résumé
As a result of advances in pharmacogenomics (PGx), the paradigm that a single dose of a drug is extrapolated to an entire population is set to change. Personalising drug prescriptions according to individual genomic determinants would make it possible to increase the effectiveness and tolerance of treatments. In Switzerland, any doctor can prescribe validated PGx tests for five actionable drugs : abacavir, carbamazepine, thiopurines [azathioprine], fluoropyrimidines [5-FU, capecitabine] and irinotecan. Such an approach presupposes that PGx data are shared with trained clinicians and that prescribing aids can guide them.