Timing stroke : a review on stroke pathophysiology and its influence over time on diffusion measures
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9 août 2022
- handle: 10670/1.76un15
- doi: 10.1016/j.jns.2022.120377
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Apoplexy Cerebrovascular disorders Cerebrovascular syndrome Brain--Blood-vessels--Diseases Cerebral circulation disorders Stroke CVA (Disease) Cerebral vascular accident Cerebrovascular accidentCiter ce document
Alberto Osa García et al., « Timing stroke : a review on stroke pathophysiology and its influence over time on diffusion measures », Papyrus : le dépôt institutionnel de l'Université de Montréal, ID : 10.1016/j.jns.2022.120377
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Résumé
Diffusion imaging (DWI) is considered an optimal technique to detect hyperacute cerebral ischemia and has thus enriched the clinical management of patients with suspected stroke. Researchers have taken this technique beyond with Diffusion Tensor Imaging (DTI)-extracted measures, which have been proposed as biomarkers of stroke progression. A large body of literature report on the correlates between pathophysiological events, such as cytotoxic and vasogenic edema, and diffusion changes in the brain. However, a unified picture of these changes, and their exploration as stroke pathology progression biomarkers, remains to be done. We present here a narrative review on the different pathophysiological events underlying stroke from onset until late subacute stages and its relation to different brain edema forms. Studies included in this review used either DWI and/or DTI analysis in hyperacute (