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3 janvier 2020
- handle: 10670/1.gsyxon
- doi: 10.1016/j.jhep.2016.01.021
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Models, MathematicalCiter ce document
Lorette Noiret et al., « Mathematical models and hepatology; oil and vinegar? », Papyrus : le dépôt institutionnel de l'Université de Montréal, ID : 10.1016/j.jhep.2016.01.021
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Mathematical models are increasingly being used in medicine to study physiological, pathophysiological and therapeutic pathways [1–3]. In hepatology, mathematical abstractions have been beneficial to predict the viral load of hepatitis C following treatment [4], outcome after acetaminophen overdose [5], or to quantify porto-systemic shunting and inter-organ ammonia metabolism at different stages of cirrhosis [6]. However, in many medical fields (including hepatology), there is much resistance to include theoretical models in their traditional tool set and furthermore a lack of confidence in the generated theoretical results.