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10 juin 2020
- handle: 10670/1.w4eccx
- doi: 10.1016/j.pnpbp.2018.03.027
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Danièle Laverdure-Dupont et al., « Placebo analgesia persists during sleep : an experimental study », Papyrus : le dépôt institutionnel de l'Université de Montréal, ID : 10.1016/j.pnpbp.2018.03.027
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Although placebo analgesia is a well-recognized phenomenon with important clinical implications, the possibility that placebo effects occur during sleep has received little attention. This experimental study examined whether responsiveness to acute heat pain stimuli applied during sleep could be reduced following a placebo conditioning procedure administered before sleep. Healthy individuals (n = 9) underwent polysomnographic recordings for one habituation night followed by one placebo analgesia night and one control night in counterbalanced order. Conditioning induced robust analgesia expectations before the placebo night. In the morning after the placebo night, participants reported less nocturnal pain, anxiety, and associated sleep disturbance (all p's