The gene–environmental architecture of the development of adolescent substance use

Fiche du document

Date

12 octobre 2018

Discipline
Type de document
Périmètre
Langue
Identifiants

Mots-clés

Substance use Adolescence Growth curve modeling Genetic and environmental influences Twin design


Citer ce document

Frank Vitaro et al., « The gene–environmental architecture of the development of adolescent substance use », Papyrus : le dépôt institutionnel de l'Université de Montréal, ID : 10.1017/S0033291718000089


Métriques


Partage / Export

Résumé 0

Background: Using a longitudinal twin design and a latent growth curve/autoregressive approach, this study examined the genetic-environmental architecture of substance use across adolescence. Methods: Self-reports of substance use (i.e., alcohol, marijuana) were collected at ages 13, 14, 15 and 17 years from 476 twin pairs (475 boys, 477 girls) living in the Province of Quebec, Canada. Substance use increased linearly across the adolescent years. Results: ACE modeling revealed that genetic, as well as shared and non-shared environmental factors explained the overall level of substance use and that these same factors also partly accounted for growth in substance use from age 13 to age 17. Additional genetic factors predicted the growth in substance use. Finally, autoregressive effects revealed age-specific nonshared environmental influences and, to a lesser degree, age-specific genetic influences, which together accounted for the stability of substance use across adolescence. Conclusions: The results support and expand the notion that genetic and environmental influences on substance use during adolescence are both developmentally stable and developmentally dynamic.

document thumbnail

Par les mêmes auteurs

Sur les mêmes sujets

Sur les mêmes disciplines

Exporter en