Obesity and Migraine: Effect Modification by Gender and Perceived Stress

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21 août 2018

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Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1159/000489663

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/29843127

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INRAE




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Valentina A. Andreeva et al., « Obesity and Migraine: Effect Modification by Gender and Perceived Stress », Archive Ouverte d'INRAE, ID : 10.1159/000489663


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Background: The association between obesity and migraine has been established; however, it is unclear whether it varies by perceived stress within each gender. Methods: This crosssectional study used data from the ongoing NutriNet-Sante e-cohort with enrollees from the general population. Anthropometric and migraine data were provided via self-report questionnaires (2013-2016). Migraine was defined using established criteria. Perceived stress was assessed with Cohen's Perceived Stress Scale-10. Associations were estimated via gender-and stress-stratified multivariable polytomous logistic regression models. Results: Among 32,835 participants with complete data (75% women; mean age = 51.9 +/- 13.8 years), 34% reported no headache, 44% non-migraine headache, and 22% migraine with or without aura during one's lifetime. In these groups, obesity was present in 8.6, 9.9, and 11.6%, respectively. Stress was a significant moderator of the obesity-migraine association only among women. The largest significant adjusted odds ratio (aOR) was found between obesity and migraine in women with high stress (aOR 1.61, 95% CI 1.35-1.91). Conclusions: We found support for gender-and stress-dependent associations between obesity and migraine using a large, heterogeneous adult sample. This underscores the need for evidence-based strategies for weight loss and stress reduction for female migraineurs.

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