Publications et données de A. Comment

Documents écrit par A. Comment (8) | parle de A. Comment (6199147)

Hyperpolarized 13C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma.

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M. Mishkovsky et al. (11 mars 2021)

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Glioblastoma (GBM) is the most aggressive brain tumor type in adults. GBM is heterogeneous, with a compact core lesion surrounded by an invasive tumor front. This front is highly relevant for tumor recurrence but is generally non-detectable using standard imaging techniques. Recent studies demonstra...

Noninvasive rapid detection of metabolic adaptation in activated human T lymphocytes by hyperpolarized 13C magnetic resonance.

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E. Can et al. (13 janv. 2020)

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The metabolic shift induced in human CD4 + T lymphocytes by stimulation is characterized by an upregulation of glycolysis, leading to an augmentation in lactate production. This adaptation has already been highlighted with various techniques and reported in several previous studies. We herein propos...

Hyperpolarized 13C Magnetic Resonance Spectroscopy Reveals the Rate-Limiting Role of the Blood-Brain Barrier in the Cerebral Uptake and Metabolism of l-Lactate in Vivo.

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Y. Takado et al. (21 nov. 2018)

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The dynamics of l-lactate transport across the blood-brain barrier (BBB) and its cerebral metabolism are still subject to debate. We studied lactate uptake and intracellular metabolism in the mouse brain using hyperpolarized 13 C magnetic resonance spectroscopy (MRS). Following the intravenous injec...

Probing cardiac metabolism by hyperpolarized 13C MR using an exclusively endogenous substrate mixture and photo-induced nonpersistent radicals.

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JAM Bastiaansen et al.

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To probe the cardiac metabolism of carbohydrates and short chain fatty acids simultaneously in vivo following the injection of a hyperpolarized 13 C-labeled substrate mixture prepared using photo-induced nonpersistent radicals. Droplets of mixed [1- 13 C]pyruvic and [1- 13 C]butyric acids were froze...

Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized 13C magnetic resonance.

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M. Mishkovsky et al. (15 sept. 2017)

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The mammalian brain relies primarily on glucose as a fuel to meet its high metabolic demand. Among the various techniques used to study cerebral metabolism, 13 C magnetic resonance spectroscopy (MRS) allows following the fate of 13 C-enriched substrates through metabolic pathways. We herein demonstr...

Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate.

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J.A. Bastiaansen et al. (6 mai 2016)

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Cardiac dysfunction is often associated with a shift in substrate preference for ATP production. Hyperpolarized (HP) (13)C magnetic resonance spectroscopy (MRS) has the unique ability to detect real-time metabolic changes in vivo due to its high sensitivity and specificity. Here a protocol using HP...

Hyperpolarized (6)Li as a probe for hemoglobin oxygenation level.

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R. Balzan et al. (2016)

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Hyperpolarization by dissolution dynamic nuclear polarization (DNP) is a versatile technique to dramatically enhance the nuclear magnetic resonance (NMR) signal intensity of insensitive long-T1 nuclear spins such as (6)Li. The (6)Li longitudinal relaxation of lithium ions in aqueous solutions strong...

Hyperpolarized lithium-6 as a sensor of nanomolar contrast agents.

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R.B. van Heeswijk et al. (2009)

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Lithium is widely used in psychotherapy. The (6)Li isotope has a long intrinsic longitudinal relaxation time T(1) on the order of minutes, making it an ideal candidate for hyperpolarization experiments. In the present study we demonstrated that lithium-6 can be readily hyperpolarized within 30 min,...

[Cahier de sermons de Jean-Louis Cabon]

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Cabon Jean-Louis (1882-1925)

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An Taolennou - V - Pempvet Taolenn

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Commentaire (résumé) d'un cinquième tableau, probablement de la série de 1936. ARZ030 contient 1 feuille collée à la page 13. ARZ028, ARZ029 et ARZ029 forment un lot.

An Taolennou - An eil Daolenn

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Jean-Louis (1898 - 1946) Rozec

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Commentaire par Jean-Louis Rozec du deuxième tableau de la première série des tableaux Montfortains réalisés par Xavier de Langlais en 1936. 17 feuillets tapés à la machine sur le recto, annotation manuscrite sur le verso du quatrième feuillet.

An Taolennou - Taolenn genta

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Jean-Louis (1898 - 1946) Rozec

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Commentaire par Jean-Louis Rozec du premier tableau de la première série des tableaux Montfortains réalisés par Xavier de Langlais en 1936. 15 feuillets tapés à la machine sur le recto, annotation manuscrite sur la première page.

Carnet d'adresses 1 de Charles Du Bos

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Charles Du Bos

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Il s'agit ici d'un des trois carnets d'adresses de Charles Du Bos qui ont été donnés au centre de ressources Jacques-Seebacher. Les deux autres carnets seront à numériser ultérieurement. Carnet d'adresses 1 Du Bos Index des noms carnet d'adresses 1 Du Bos Annexe 1 Annexe 2 Annexe 3 Annexe 4 Index d...

Carnet d'adresses 3 de Charles Du Bos

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Charles Du Bos

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Il s'agit du troisième carnet d'adresses de Charles Du Bos qui a été donné au centre de ressources Jacques-Seebacher. Le premier carnet a été numérisé et est disponible sur la bibliothèque numérique. Le deuxième carnet sera a numérisé ultérieurement.