Long-term daylight deprivation such as during the Antarctic winter has been shown to lead to delayed sleep timing and sleep fragmentation. We aimed at testing whether retinal sensitivity, sleep and circadian rest-activity will change during long-term daylight deprivation on two Antarctic bases (Conc...

The genomic landscape of human cellular circadian variation points to a novel role for the signalosome.

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L. Gaspar et al. (4 sept. 2017)

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The importance of natural gene expression variation for human behavior is undisputed, but its impact on circadian physiology remains mostly unexplored. Using umbilical cord fibroblasts, we have determined by genome-wide association how common genetic variation impacts upon cellular circadian functio...

D. Kunz Westerhoff & M. Atallah (dir.), L'Homme-machine et ses avatars. Entre science, philosophie et littérature XVIIe-XXIe siècle

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