Emmanuel Moreau

Discipline

Sociologie (1) Psychologie (1) Economies et finances (1)

Type de document

Autres (13) Articles (2)

Co-auteur

Date

Source

Mot-clé

Colchicine (9) Drugs (9) Agent (Philosophy) (9) Microtubules (8) Cancer (7) Derivatives (6) cancer (5) Cancer (5) Tubulins (5) Ligands (5) Inhibition (5) Design (5) Cells (5) Cell lines (5) Cell cycle (5) Antineoplastic agents (5) Design (5) spectacle (4) protéine (4) effet (4) pièce d'exposition (4) Development (4) Alkylating agents (4) Molecules (4) Arrest (4) Antimitotic agents (4) toxicité (3) membrane (3) analyse (3) Series (3)

Documents écrit par Emmanuel Moreau (15) | parle de Emmanuel Moreau (0)

Homologation of the alkyl sidechain of antimitotic phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonate prodrugs selectively targeting CYP1A1-expressing breast cancers improves their stability in rodent liver microsomes
Atziri Corin Chavez Alvarez et al.
Le 190 cumple trece años: La experiencia del primer centro de salud sexual de Francia
Thibaut Jedrzejewski et al. (2023)
Le 190 a treize ans : l’expérience du premier centre de santé sexuelle français
Thibaut Jedrzejewski et al. (2023)
Synthesis, antiproliferative activity evaluation and structure-activity relationships of novel aromatic urea and amide analogues of N-phenyl-N’-(2-chloroethyl)ureas
Sébastien Fortin et al.
N-Phenyl-N’-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. part 3 : role of carbonyl group
Sébastien Fortin et al.
Intramolecular cyclization of N-phenyl N’(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating b-tubulin Glu198 and prohibitin Asp40
Anna Trzeciakiewicz et al.
Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships
Sébastien Fortin et al.
Design, synthesis, biological evaluation and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4
Sébastien Fortin et al.
Characterization of the covalent binding of N-phenyl-N'-(2-chloroethyl)ureas to β-tubulin : importance of glutamic acid 198 in microtubule stability
Sébastien Fortin et al.
Quick and simple detection technique to assess the binding of antimicrotubule agents to the colchicine-binding site
Sébastien Fortin et al.
N-Phenyl-N′-(2-chloroethyl)ureas (CEU) as potential antineoplastic agents. Part 2 : role of ω-hydroxyl group in the covalent binding to β-tubulin
Sébastien Fortin et al.
Optimized N-phenyl-N'-(2-chloroethyl)ureas as potential antineoplastic agents: synthesis and growth inhibition activity
Sébastien Fortin et al.
N-Phenyl-N'-(2-chloroethyl)urea analogues of combretastatin A-4: Is the N-phenyl-N'-(2-chloroethyl)urea pharmacophore mimicking the trimethoxy phenyl moiety ?
Sébastien Fortin et al.
Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between a- and b-tubulin
Sébastien Fortin et al.
A comparative molecular field and comparative molecular similarity indices analyses (CoMFA and CoMSIA) of N-phenyl-N'-(2-chloroethyl)urea targeting the colchicine-binding site as anticancer agents
Sébastien Fortin et al.