Sébastien Fortin

Discipline

Psychologie (3) Sciences de l'information et de la communication (1) Economies et finances (1)

Type de document

Autres (42)

Co-auteur

Source

Mot-clé

Cancer (26) Cancer (24) cancer (23) Antineoplastic agents (22) Cell cycle (19) Agent (Philosophy) (19) Cells (18) Microtubules (17) roman (17) spectacle (16) Derivatives (16) Colchicine (15) Cell lines (15) Addition (15) Evaluation (14) évaluation (13) Evaluation (13) Drugs (13) Breast (13) Design (13) Synthesis (13) Design (12) effet (11) Development (11) Inhibitors (11) Cancer cells (11) Arrest (11) Toxicology (11) toxicité (10) pièce d'exposition (10)

Documents écrit par Sébastien Fortin (42) | parle de Sébastien Fortin (0)

Homologation of the alkyl sidechain of antimitotic phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonate prodrugs selectively targeting CYP1A1-expressing breast cancers improves their stability in rodent liver microsomes
Atziri Corin Chavez Alvarez et al.
Development of a novel UHPLC-UV method for quantification of three phenyl 4‑(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates in CD-1® IGS female mouse plasma
Atziri Corin Chavez Alvarez et al.
4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamide salts: novel hydrosoluble prodrugs of antimitotics selectively bioactivated by the cytochrome P450 1A1 in breast cancer cells
Vincent Ouellette et al.
Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells
Vincent Ouellette et al.
N-Phenyl ureidobenzenesulfonates, a novel class of human dihydroorotate dehydrogenase inhibitors inducing differentiation and apoptosis in acute myeloid leukemia cells
Chahrazed Bouzriba et al.
Design, synthesis and biological evaluation of new 2,6-difluorinated phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new antimicrotubule agents
Chahrazed Bouzriba et al.
Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site
Vincent Ouellette et al.
Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups
Alexis Paquin et al.
N-Phenyl ureidobenzenesulfonates, a novel class of promising human dihydroorotate dehydrogenase inhibitors
Sébastien Fortin et al.
Phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonates and phenyl 4-(2-oxopyrrolidin-1-yl)benzenesulfonamides as new antimicrotubule agents targeting the colchicine-binding site
Sébastien Fortin et al.
Effectiveness of adjuvant carboplatin-based chemotherapy compared to cisplatin in non-small cell lung cancer
Valérie Couillard-Montminy et al.
Stereoselective synthesis of fluorinated galactopyranosides as potential molecular probes for galactophilic proteins : assessment of monofluorogalactoside–LecA interactions
Sébastien Fortin et al.
Evaluation of the time-dependent antiproliferative activity and liver microsome stability of 3 phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as promising CYP1A1-dependent antimicrotubule prodrugs
Mitra Zarifi Khosroshahi et al.
4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides as new antimitotic prodrugs activated by cytochrome P450 1A1 in breast cancer cells
Atziri Corin Chavez Alvarez et al.
Preparation, characterisation and biological evaluation of new N-phenyl amidobenzenesulfonates and N-phenyl ureidobenzenesulfonates inducing DNA double-strand breaks. Part 3. Modulation of ring A
Sébastien Fortin et al.
Synthesis, antiproliferative activity evaluation and structure-activity relationships of novel aromatic urea and amide analogues of N-phenyl-N’-(2-chloroethyl)ureas
Sébastien Fortin et al.
N-Phenyl-N’-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. part 3 : role of carbonyl group
Sébastien Fortin et al.
Synthesis and biological evaluation of novel N-phenyl ureidobenzenesulfonate derivatives as potential anticancer agents. Part 2. Modulation of the ring B
Sébastien Fortin et al.
Diversity‐oriented synthesis of diol‐based peptidomimetics as potential HIV protease inhibitors and antitumor agents
Sébastien Fortin et al.
Activation of phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonates prodrugs by CYP1A1 as new antimitotics targeting breast cancer cells
Sébastien Fortin et al.
Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks
Sébastien Fortin et al.
Styryl-N-phenyl-N'-(2-chloroethyl)ureas and styrylphenylimidazolidin-2-ones as new potent microtubule-disrupting agents using combretastatin A-4 as model
Sébastien Fortin et al.
New testosterone derivatives as semi-synthetic anticancer agents against prostate cancer : synthesis and preliminary biological evaluation
Nathalie Morin et al.
New platinum(II) complexes conjugate at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer : design, synthesis, structure-activity relationships and biological evaluation
Sébastien Fortin et al.
Advances in the development of hybrid anticancer drugs
Sébastien Fortin et al.

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