Effects of MRI scan acceleration on brain volume measurement consistency.

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2012

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info:eu-repo/semantics/altIdentifier/doi/10.1002/jmri.23694

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info:eu-repo/semantics/altIdentifier/pmid/22570196

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info:eu-repo/semantics/altIdentifier/eissn/1522-2586

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_288ECB5924F39

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Diseases--Imaging

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G. Krueger et al., « Effects of MRI scan acceleration on brain volume measurement consistency. », Serveur académique Lausannois, ID : 10.1002/jmri.23694


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PURPOSE: To evaluate the effects of recent advances in magnetic resonance imaging (MRI) radiofrequency (RF) coil and parallel imaging technology on brain volume measurement consistency. MATERIALS AND METHODS: In all, 103 whole-brain MRI volumes were acquired at a clinical 3T MRI, equipped with a 12- and 32-channel head coil, using the T1-weighted protocol as employed in the Alzheimer's Disease Neuroimaging Initiative study with parallel imaging accelerations ranging from 1 to 5. An experienced reader performed qualitative ratings of the images. For quantitative analysis, differences in composite width (CW, a measure of image similarity) and boundary shift integral (BSI, a measure of whole-brain atrophy) were calculated. RESULTS: Intra- and intersession comparisons of CW and BSI measures from scans with equal acceleration demonstrated excellent scan-rescan accuracy, even at the highest acceleration applied. Pairs-of-scans acquired with different accelerations exhibited poor scan-rescan consistency only when differences in the acceleration factor were maximized. A change in the coil hardware between compared scans was found to bias the BSI measure. CONCLUSION: The most important findings are that the accelerated acquisitions appear to be compatible with the assessment of high-quality quantitative information and that for highest scan-rescan accuracy in serial scans the acquisition protocol should be kept as consistent as possible over time. J. Magn. Reson. Imaging 2012;36:1234-1240. ©2012 Wiley Periodicals, Inc.

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