On the accuracy and precision of cardiac magnetic resonance T2 mapping: A high-resolution radial study using adiabatic T2 preparation at 3 T.
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- doi: 10.1002/mrm.26107
- issn: 0740-3194
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W. Bano et al., « On the accuracy and precision of cardiac magnetic resonance T2 mapping: A high-resolution radial study using adiabatic T2 preparation at 3 T. », Serveur académique Lausannois, ID : 10.1002/mrm.26107
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The goal of this study was to characterize the accuracy and precision of cardiac T2 mapping as a function of different factors including low signal-to-noise ratio (SNR), imaging in systole, and off-resonance frequencies. Bloch equation and Monte Carlo simulations were used to determine the influence of SNR and the choice of T2 preparation echo time (TET2prep ) increments on the accuracy and precision of high-resolution radial cardiac T2 mapping at 3.0 T. Healthy volunteers were scanned to establish the difference in precision and inter- and intraobserver variability between T2 mapping in diastole and systole, as well as the effect of SNR and off-resonance frequencies on the accuracy of T2 maps. The simulations demonstrated that a TET2prep increment of ∼0.75 times the T2 value of interest optimally increases the precision of the T2 fit. Systolic T2 maps were found to have a higher precision (P = 0.002), but similar inter- and intraobserver variability compared with diastolic T2 maps, whereas off-resonance frequencies beyond ± 100 Hz cause a significant decrease in both accuracy and precision (P