Fiche du document
2009
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1007/s00414-009-0331-1
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/19241086
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pissn/1437-1596[electronic]
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_3F08F309B4473
info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer
Sujets proches
Cadavers Remains, Human Corpses Human remains DeceasedCiter ce document
V. Castella et al., « One person with two DNA profiles: a(nother) case of mosaicism or chimerism. », Serveur académique Lausannois, ID : 10.1007/s00414-009-0331-1
Métriques
Partage / Export
Résumé
Nuclear DNA markers, such as short tandem repeats (STR), are widely used for crime investigation and paternity testing. STR were used to determine whether a piece of tissue regurgitated by a dog was part of the penis of a dead, emasculated, man. Unexpectedly, when analyzing the recovered material and a blood sample from the deceased, five out of the 18 loci differed. According to the results, one could have concluded that these samples originated from two different persons. However, taking into account contextual information and data from complementary genetic analyses, the most likely hypothesis was that the deceased was a genetic mosaic or a chimera. Within a forensic genetic context, such genetic peculiarities may prevent associating the perpetrator of an offense with a stain left at a crime scene or lead to false paternity exclusions. Fast recognition of mosaics or chimeras, adapted sampling scheme, as well as careful interpretation of the data should allow avoiding such pitfalls.