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2013
- doi: 10.1007/s00414-013-0870-3
- issn: 0937-9827
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Vehicle bodies Worth Axiology Measuring Mensuration Type 1 diabetes Brittle diabetes IDDM (Disease) Ketosis prone diabetes Diabetes mellitus Insulin-dependent diabetes Death--Philosophy Dying End of life Biological chemistry Physiological chemistry Chemical composition of organisms Organisms--Composition Post-mortem examinations Necroscopy Postmortems Necropsy Postmortem examinationsCiter ce document
C. Palmiere et al., « Preliminary results on the postmortem measurement of 3-beta-hydroxybutyrate in liver homogenates. », Serveur académique Lausannois, ID : 10.1007/s00414-013-0870-3
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The concentrations of 3-beta-hydroxybutyrate (3HB) in blood and two liver samples were retrospectively examined in a series of medicolegal autopsies. These cases included diabetic ketoacidosis, nondiabetic individuals presenting moderate to severe decompositional changes and nondiabetic medicolegal cases privy of decompositional changes. 3HB concentrations in liver sample homogenates correlate well with blood values in all examined groups. Additionally, decompositional changes were not associated with increases in blood and liver 3HB levels. These results suggest that 3HB can be reliably measured in liver homogenates when blood is not available at autopsy. Furthermore, they suggest that metabolic disturbances potentially leading or contributing to death may be objectified through liver 3HB determination even in decomposed bodies.
