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2003
- doi: 10.1007/s00467-003-1179-0
- issn: 0931-041X
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Immune depression Immune suppression Suppression, Immune Depression, Immune ImmunodepressionCiter ce document
F. Cachat et al., « Lymphomatoid granulomatosis in a renal transplant patient. », Serveur académique Lausannois, ID : 10.1007/s00467-003-1179-0
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Lymphomatoid granulomatosis is a rare angiocentric and angiodestructive pulmonary angiitis considered as a variant of the lymphoproliferative disorder group. Patients with organ transplantation are at an increased risk for post-transplant lymphoproliferative disorders secondary to their immunosuppression. However, lymphomatoid granulomatosis has rarely been described in patients with renal transplantation. It often presents with severe pulmonary signs. We describe a case whose initial presentation was an isolated VIth nerve palsy. We review the radiological and pathological findings and discuss the etiopathogenesis and therapeutic options of this particular lymphoproliferative disorder. With careful and stepwise reduction in her immunosuppression, our patient showed a complete disappearance of her lymphomatoid granulomatosis, and she is clinically well more than 3 years after the diagnosis, with good kidney function.