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8 février 2021
- doi: 10.1016/j.ccell.2021.01.015
- issn: 1535-6108
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Thymus-dependent lymphocytes Thymus-derived cells T lymphocytes Thymus-dependent cellsCiter ce document
W. Held et al., « Not All Tumor-Infiltrating CD8+ T Cells Are Created Equal. », Serveur académique Lausannois, ID : 10.1016/j.ccell.2021.01.015
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Résumé
Adoptive cell immunotherapy using in vitro expanded autologous tumor-infiltrating lymphocytes has the potential to mediate durable remission of certain types of cancer. A recent paper in Science shows that complete and durable control of metastatic melanoma requires the infusion of tumor-specific CD8 + T cells that have stem-cell-like properties.