14 mars 2022
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W. Held et al., « Stem-cell-like T cells have a specific entry gate to the tumor. », Serveur académique Lausannois, ID : 10.1016/j.ccell.2022.02.004
Tumor-infiltrated T cells with stem-cell-like properties are important for determining the immunotherapy response. In this issue of Cancer Cell, Asrir and colleagues show that their entry requires specialized tumor-associated endothelial cells that resemble immature and inflamed lymph node vessels and that immunotherapy enhances the recruitment capacity of these endothelial cells.