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- doi: 10.1016/j.clnu.2017.01.009
- issn: 0261-5614
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Energy resources Power supply Energy Energy Conservation of energy Correlation of forces EnergyCiter ce document
L. Pradelli et al., « Supplemental parenteral nutrition in intensive care patients: A cost saving strategy. », Serveur académique Lausannois, ID : 10.1016/j.clnu.2017.01.009
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The Swiss supplemental parenteral nutrition (SPN) study demonstrated that optimised energy provision combining enteral nutrition (EN) and SPN reduces nosocomial infections in critically ill adults who fail to achieve targeted energy delivery with EN alone. To assess the economic impact of this strategy, we performed a cost-effectiveness analysis using data from the SPN study. Multivariable regression analyses were performed to characterise the relationships between SPN, cumulative energy deficit, nosocomial infection, and resource consumption. The results were used as inputs for a deterministic simulation model evaluating the cost-effectiveness of SPN administered on days 4-8 in patients who fail to achieve ≥60% of targeted energy delivery with EN by day 3. Cost data were derived primarily from Swiss diagnosis-related case costs and official labour statistics. Provision of SPN on days 4-8 was associated with a mean decrease of 2320 ± 338 kcal in cumulative energy deficit compared with EN alone (p