A new self-expanding aortic stent valve with annular fixation: in vitro haemodynamic assessment.

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2009

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info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ejcts.2009.01.052

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info:eu-repo/semantics/altIdentifier/pmid/19409805

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info:eu-repo/semantics/altIdentifier/pissn/1873-734X[electronic]

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_D084D98852983

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Prosthetic heart valves

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M. Vergnat et al., « A new self-expanding aortic stent valve with annular fixation: in vitro haemodynamic assessment. », Serveur académique Lausannois, ID : 10.1016/j.ejcts.2009.01.052


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OBJECTIVE: Balloon-expandable stent valves require flow reduction during implantation (rapid pacing). The present study was designed to compare a self-expanding stent valve with annular fixation versus a balloon-expandable stent valve. METHODS: Implantation of a new self-expanding stent valve with annular fixation (Symetis, Lausanne, Switzerland) was assessed versus balloon-expandable stent valve, in a modified Dynatek Dalta pulse duplicator (sealed port access to the ventricle for transapical route simulation), interfaced with a computer for digital readout, carrying a 25 mm porcine aortic valve. The cardiovascular simulator was programmed to mimic an elderly woman with aortic stenosis: 120/85 mmHg aortic pressure, 60 strokes/min (66.5 ml), 35% systole (2.8 l/min). RESULTS: A total of 450 cardiac cycles was analysed. Stepwise expansion of the self-expanding stent valve with annular fixation (balloon-expandable stent valve) resulted in systolic ventricular increase from 120 to 121 mmHg (126 to 830+/-76 mmHg)*, and left ventricular outflow obstruction with mean transvalvular gradient of 11+/-1.5 mmHg (366+/-202 mmHg)*, systolic aortic pressure dropped distal to the valve from 121 to 64.5+/-2 mmHg (123 to 55+/-30 mmHg) N.S., and output collapsed to 1.9+/-0.06 l/min (0.71+/-0.37 l/min* (before complete obstruction)). No valve migration occurred in either group. (*=p

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