Blood pressure changes after renal denervation at 10 European expert centers.

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2014

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info:eu-repo/semantics/altIdentifier/doi/10.1038/jhh.2013.88

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info:eu-repo/semantics/altIdentifier/pmid/24067345

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info:eu-repo/semantics/altIdentifier/eissn/1476-5527

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_69AD7F6282354

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A. Persu et al., « Blood pressure changes after renal denervation at 10 European expert centers. », Serveur académique Lausannois, ID : 10.1038/jhh.2013.88


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We did a subject-level meta-analysis of the changes (Δ) in blood pressure (BP) observed 3 and 6 months after renal denervation (RDN) at 10 European centers. Recruited patients (n=109; 46.8% women; mean age 58.2 years) had essential hypertension confirmed by ambulatory BP. From baseline to 6 months, treatment score declined slightly from 4.7 to 4.4 drugs per day. Systolic/diastolic BP fell by 17.6/7.1 mm Hg for office BP, and by 5.9/3.5, 6.2/3.4, and 4.4/2.5 mm Hg for 24-h, daytime and nighttime BP (P0.03 for all). In 47 patients with 3- and 6-month ambulatory measurements, systolic BP did not change between these two time points (P0.08). Normalization was a systolic BP of

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