Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness.

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Date

8 mars 2017

Type de document
Périmètre
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Serveur académique Lausannois

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Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1038/ncomms14694

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/28272467

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/eissn/2041-1723

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_718B98CBA9DB7

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Serveur Académique Lausannois

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Université de Lausanne et CHUV

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info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer

Mots-clés 0

3-Oxo-5-alpha-Steroid 4-Dehydrogenase/genetics; Adipogenesis/genetics; Alopecia/genetics; Case-Control Studies; Fibroblast Growth Factor 5/genetics; Genetic Association Studies; Genome-Wide Association Study; Genotype; Humans; Intercellular Signaling Peptides and Proteins/genetics; Interferon Regulatory Factors/genetics; Male; Melatonin; Membrane Proteins/genetics; Phenotype; Signal Transduction/genetics; Trans-Activators/genetics

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Alopecia Loss of hair Hair loss

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S. Heilmann-Heimbach et al., « Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness. », Serveur académique Lausannois, ID : 10.1038/ncomms14694

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Male-pattern baldness (MPB) is a common and highly heritable trait characterized by androgen-dependent, progressive hair loss from the scalp. Here, we carry out the largest GWAS meta-analysis of MPB to date, comprising 10,846 early-onset cases and 11,672 controls from eight independent cohorts. We identify 63 MPB-associated loci (P

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