Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

B. Benyamin; T. Esko; J.S. Ried; A. Radhakrishnan; S.H. Vermeulen; M. Traglia; M. Gögele; D. Anderson; L. Broer; C. Podmore; J. Luan; Z. Kutalik; S. Sanna; P. van der Meer; T. Tanaka; F. Wang; H.J. Westra; L. Franke; E. Mihailov; L. Milani; J. Häldin; J. Winkelmann; T. Meitinger; J. Thiery; A. Peters; M. Waldenberger; A. Rendon; J. Jolley; J. Sambrook; L.A. Kiemeney; F.C. Sweep; C.F. Sala; C. Schwienbacher; I. Pichler; J. Hui; A. Demirkan; A. Isaacs; N. Amin; M. Steri; G. Waeber; N. Verweij; J.E. Powell; D.R. Nyholt; A.C. Heath; P.A. Madden; P.M. Visscher; M.J. Wright; G.W. Montgomery; N.G. Martin; D. Hernandez; S. Bandinelli; P. van der Harst; M. Uda; P. Vollenweider; R.A. Scott; C. Langenberg; N.J. Wareham; C. van Duijn; J. Beilby; P.P. Pramstaller; A.A. Hicks; W.H. Ouwehand; K. Oexle; C. Gieger; A. Metspalu; C. Camaschella; D. Toniolo; D.W. Swinkels; J.B. Whitfield

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

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doi: 10.1038/ncomms5926
issn: 2041-1723

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Serveur académique Lausannois

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info:eu-repo/semantics/altIdentifier/doi/10.1038/ncomms5926

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info:eu-repo/semantics/altIdentifier/pmid/25352340

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info:eu-repo/semantics/altIdentifier/eissn/2041-1723

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_8AB33C82AD707

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Serveur Académique Lausannois

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Université de Lausanne et CHUV

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info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer

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Bronze diabetes Hemachromatosis Iron storage disease Hematochromatosis Diabetes, Bronze Recklinghausen-Applebaum disease Haemochromatosis

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B. Benyamin et al., « Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis », Serveur académique Lausannois, ID : 10.1038/ncomms5926

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Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional cohorts (total up to 48,972 subjects). We find 11 genome-wide-significant (P

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Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

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