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19 juillet 2017
- doi: 10.1038/s41467-017-00031-7
- issn: 2041-1723
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Group dynamics Association Groups, Social Inheritance (Biology) Pangenesis Ancestry Descent Genealogy--Handbooks, manuals, etc Genealogical research Family trees Genealogy--Sources Genealogy--History Family history (Genealogy) Genealogy--Research Ancestry Descent Pedigrees Genealogy--Methodology Biography--Ancestry Relations with family Biography--Descendants Biography--Family AncestryCiter ce document
M.C. Zillikens et al., « Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. », Serveur académique Lausannois, ID : 10.1038/s41467-017-00031-7
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Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330) measured using dual energy X-ray absorptiometry or bioelectrical impedance analysis, adjusted for sex, age, height, and fat mass. Twenty-one single-nucleotide polymorphisms were significantly associated with lean body mass either genome wide (p