Fiche du document
- doi: 10.1080/14992027.2022.2056721
- issn: 1499-2027
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1080/14992027.2022.2056721
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/35510657
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/eissn/1708-8186
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_2ACA564D1A621
info:eu-repo/semantics/openAccess , CC BY-NC-ND 4.0 , https://creativecommons.org/licenses/by-nc-nd/4.0/
Sujets proches
Immunisation Hearing lossCiter ce document
P. Ekobena et al., « Four cases of audio-vestibular disorders related to immunisation with SARS-CoV-2 mRNA vaccines. », Serveur académique Lausannois, ID : 10.1080/14992027.2022.2056721
Métriques
Partage / Export
Résumé
To gain medical insight into the clinical course and safety of otolaryngologic disorders following immunisation with severe acute respiratory coronavirus (SARS-CoV-2) mRNA-based vaccines. Case description. We report four cases of transient audio-vestibular symptoms, which occurred shortly after inoculation of two BNT162b2 (Pfizer-BioNTech ® ) and mRNA-1273 (Moderna®) vaccines. Hearing loss was unilateral in all cases and recovered at least partially: it was associated with persistent gait instability in two cases, after 1 and 7 months. Trigger mechanisms underpinning audio-vestibular impairment remain uncertain. Immune tolerance mechanisms with off-target innate activation of T-lymphocytes may be involved in vestibulocochlear nerve disorders, as for other cranial nerves involvement. The occurrence of audio-vestibular manifestations following mRNA-based vaccines needs ENT monitoring to support their causality in such rare vaccine-related adverse events. Audio-vestibular disorders appeared of transitory nature, including hearing loss, and should not deter further efforts in large-scale vaccination campaigns against SARS-CoV-2.