2018
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info:eu-repo/semantics/altIdentifier/doi/10.1080/23723556.2017.1409862
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info:eu-repo/semantics/altIdentifier/pmid/30263936
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info:eu-repo/semantics/altIdentifier/pissn/2372-3556
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_31B3469F93CE4
info:eu-repo/semantics/openAccess , CC BY-NC-ND 4.0 , https://creativecommons.org/licenses/by-nc-nd/4.0/
L. Fajas et al., « CDK4, a new metabolic sensor that antagonizes AMPK. », Serveur académique Lausannois, ID : 10.1080/23723556.2017.1409862
Cyclin-dependent kinase 4 (CDK4) is a positive regulator of cell cycle progression, however, there is growing evidence demonstrating that its function exceeds the control of cell division. Here we show that CDK4 is an important regulator of cellular substrate utilization through direct inhibition of the metabolic regulator AMPK (AMP-activated protein kinase).