Thyroid Dysfunction and Anemia: A Prospective Cohort Study and a Systematic Review.

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Serveur académique Lausannois

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info:eu-repo/semantics/altIdentifier/doi/10.1089/thy.2017.0480

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info:eu-repo/semantics/altIdentifier/pmid/29631476

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info:eu-repo/semantics/altIdentifier/eissn/1557-9077

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_5A7CEA72696B9

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Serveur Académique Lausannois

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Université de Lausanne et CHUV

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info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer

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Aged; Anemia/blood; Anemia/complications; Anemia/physiopathology; Cohort Studies; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Prospective Studies; Thyroid Diseases/blood; Thyroid Diseases/complications; Thyroid Diseases/physiopathology; Thyroid Function Tests; Thyroid Gland/physiopathology; Thyrotropin/blood; Thyroxine/blood; anemia; clinical relevance; hemoglobin; prospective population-based cohort; thyroid dysfuntion; thyrotropin

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Anaemia

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C. Floriani et al., « Thyroid Dysfunction and Anemia: A Prospective Cohort Study and a Systematic Review. », Serveur académique Lausannois, ID : 10.1089/thy.2017.0480

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Even though the association between thyroid dysfunction and anemia is commonly described, it is not known whether it is clinically relevant. This study set out to quantify the association of thyroid dysfunction on hemoglobin (Hb) concentration and risk of anemia. A systematic review (MEDLINE and EMBASE, from inception until May 15, 2017) was conducted to interpret the findings in context. Participants from the EPIC-Norfolk cohort with available baseline thyrotropin (TSH), free thyroxine (fT4), and Hb were included. Euthyroidism was defined as TSH 0.45-4.49 mIU/L (reference category), hypothyroidism as TSH ≥4.50 mIU/L (subclinical [SHypo] with normal fT4 or overt [OHypo] with low fT4), and hyperthyroidism as TSH ≤0.44 mIU/L (subclinical [SHyper] with normal fT4 or overt [OHyper] with elevated fT4). Anemia was defined as Hb

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