Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis.
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2015
- doi: 10.1093/cid/ciu795
- issn: 1058-4838
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TB (Disease) Phthisis Lungs--Tuberculosis Consumption (Disease) Pulmonary tuberculosisCiter ce document
V. Rozot et al., « Combined Use of Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis. », Serveur académique Lausannois, ID : 10.1093/cid/ciu795
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Résumé
Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection.