2012
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1093/ckj/sfs067
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pissn/2048-8505
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/eissn/2048-8513
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_C909A46141DC3
info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer
D. Renard et al., « Late onset tacrolimus-induced life-threatening polyneuropathy in a kidney transplant recipient patient », Serveur académique Lausannois, ID : 10.1093/ckj/sfs067
A 59-year-old kidney recipient was diagnosed with a late onset of severe chronic inflammatory demyelinating polyradiculoneuropathy and almost fully recovered after stopping tacrolimus and one course of intravenous immunoglobulin treatment. Unique features of this patient are the unusually long time lapse between initiation of tacrolimus and the adverse effect (10 years), a strong causality link and several arguments pointing toward an inflammatory etiology. When facing new neurological signs and symptoms in graft recipients, it is important to bear in mind the possibility of a drug-induced adverse event. Discontinuation of the suspect drug and immunomodulation are useful treatment options.