The role of migration and domestic transmission in the spread of HIV-1 non-B subtypes in Switzerland.

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2011

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info:eu-repo/semantics/altIdentifier/doi/10.1093/infdis/jir491

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info:eu-repo/semantics/altIdentifier/pmid/21881125

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info:eu-repo/semantics/altIdentifier/eissn/1537-6613

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_84330699B06F2

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V. von Wyl et al., « The role of migration and domestic transmission in the spread of HIV-1 non-B subtypes in Switzerland. », Serveur académique Lausannois, ID : 10.1093/infdis/jir491


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BACKGROUND: By analyzing human immunodeficiency virus type 1 (HIV-1) pol sequences from the Swiss HIV Cohort Study (SHCS), we explored whether the prevalence of non-B subtypes reflects domestic transmission or migration patterns. METHODS: Swiss non-B sequences and sequences collected abroad were pooled to construct maximum likelihood trees, which were analyzed for Swiss-specific subepidemics, (subtrees including ≥80% Swiss sequences, bootstrap >70%; macroscale analysis) or evidence for domestic transmission (sequence pairs with genetic distance

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