Glucose-containing peritoneal dialysis fluids regulate leptin secretion from 3T3-L1 adipocytes

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_A442C9C6B35C4

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D. Teta et al., « Glucose-containing peritoneal dialysis fluids regulate leptin secretion from 3T3-L1 adipocytes », Serveur académique Lausannois, ID : 10.1093/ndt/gfh812


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BACKGROUND: A marked elevation of serum leptin is observed soon after the start of peritoneal dialysis (PD), suggesting that leptin production may be stimulated by this treatment. Glucose metabolism is the major factor regulating leptin. The current study was designed to test if glucose-based PD fluids might regulate leptin production in vitro. METHODS: 3T3-L1 adipocytes were exposed to a 50:50 mixture of dialysis solutions and medium M199 containing 10% serum for

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