Κey Role of Early Source Control in Candidemic Patients With Sepsis or Septic Shock.

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info:eu-repo/semantics/altIdentifier/doi/10.1093/ofid/ofac383

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_16BC39E44CF12

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info:eu-repo/semantics/openAccess , CC BY-NC-ND 4.0 , https://creativecommons.org/licenses/by-nc-nd/4.0/




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M. Papadimitriou-Olivgeris et al., « Κey Role of Early Source Control in Candidemic Patients With Sepsis or Septic Shock. », Serveur académique Lausannois, ID : 10.1093/ofid/ofac383


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Despite advances in diagnostic and therapeutic approaches, candidemia remains associated with high mortality rates. This study aimed at identifying predictors of mortality among patients with candidemia, with a focus on early interventions that can improve prognosis. This was a single-center retrospective study including all adult patients with at least 1 positive blood culture for Candida species from 2014 to 2021. A total of 222 episodes of candidemia were included. Most candidemias were of unknown origin (36%) or vascular catheter related (29%). Septic shock developed in 29% episodes. Overall, 14-day mortality rate was 23%. In univariate analyses, septic shock was associated with higher 14-day mortality, whereas catheter-related candidemia and early (

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