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2014
- doi: 10.1155/2014/821920
- issn: 2090-004X
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info:eu-repo/semantics/altIdentifier/doi/10.1155/2014/821920
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info:eu-repo/semantics/altIdentifier/pmid/24868456
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info:eu-repo/semantics/altIdentifier/pissn/2090-004X
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_021744C224350
info:eu-repo/semantics/openAccess , CC BY 4.0 , https://creativecommons.org/licenses/by/4.0/
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V.F. Diakonis et al., « Long term followup of photorefractive keratectomy with adjuvant use of mitomycin C. », Serveur académique Lausannois, ID : 10.1155/2014/821920
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Purpose. To study the long term refractive and visual outcomes of photorefractive keratectomy (PRK) with intraoperative application of mitomycin C (MMC). Methods. This study included 37 eyes who received myopic PRK; after photoablation, a sponge soaked in 0.02% MMC solution was applied in all corneas for 2 minutes. Efficacy, safety, predictability, and stability of PRK MMC were evaluated. Endothelial cell density was evaluated at the last postoperative interval. Results. Mean preoperative spherical equivalent (SEQ) was -6.03 ± 1.87 D (diopters) and reduced to -0.09 ± 0.53 D at the last postoperative examination. Mean followup was 44.73 ± 18.24 months. All the eyes were in the ±1.00 D of attempted versus achieved SEQ at the one-year follow-up interval. Furthermore, 95% of the eyes did not lose lines or gained 1 to 2 lines of CDVA, while 5% lost 1 line. At the third postoperative month, 89% of the eyes either were clear or had trace haze, while 4 eyes had mild haze; by the 12-month postoperative interval, none of the eyes demonstrated haze. Mean endothelial cell density (ECD) at the last postoperative interval was 2658 ± 153 cells/mm(2). Conclusions. PRK, with intraoperative use of MMC, demonstrates stable refractive and visual outcomes up to 44 months after surgery.