The Influence of Breastfeeding, Cesarean Section, Pet Animals, and Urbanization on the Development of Inflammatory Bowel Disease: Data from the Swiss IBD Cohort Study.
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- doi: 10.1159/000509058
- issn: 2296-9365
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_07B8FCE48E672
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S.A. Lautenschlager et al., « The Influence of Breastfeeding, Cesarean Section, Pet Animals, and Urbanization on the Development of Inflammatory Bowel Disease: Data from the Swiss IBD Cohort Study. », Serveur académique Lausannois, ID : 10.1159/000509058
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The pathophysiology of inflammatory bowel disease (IBD) is incompletely understood. Current concepts imply that environmental factors (EFs) trigger disease onset as well as flares in genetically susceptible individuals. The objective of this study is to analyze the association between IBD and various EFs, which may influence the pathogenesis of the disease. 2,294 patients from the Swiss IBD Cohort Study (SIBDCS) received a questionnaire regarding EF including mode of delivery, breastfeeding, animals in household, and place of residence. The control group comprised patients' childhood friends, who grew up in a similar environment ("friends cohort"). A total of 1,111 questionnaires were returned from SIBDCS patients (response rate: 48.4%). Breastfeeding for