Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study.
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2009
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info:eu-repo/semantics/altIdentifier/doi/10.1161/ATVBAHA.109.186783
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info:eu-repo/semantics/altIdentifier/pmid/19372460
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_C1F779AD88266
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Blood--Serum Blood serum Wellness Personal health Older persons Older adults Seniors (Older people) Elderly people Old people Senior citizens Aging people Aged Biography--HealthCiter ce document
J. Butler et al., « Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) study. », Serveur académique Lausannois, ID : 10.1161/ATVBAHA.109.186783
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OBJECTIVE: Resistin is associated with inflammation and insulin resistance and exerts direct effects on myocardial cells including hypertrophy and altered contraction. We investigated the association of serum resistin concentrations with risk for incident heart failure (HF) in humans. METHODS AND RESULTS: We studied 2902 older persons without prevalent HF (age, 73.6+/-2.9 years; 48.1% men; 58.8% white) enrolled in the Health, Aging, and Body Composition (Health ABC) Study. Correlation between baseline serum resistin concentrations (20.3+/-10.0 ng/mL) and clinical variables, biochemistry panel, markers of inflammation and insulin resistance, adipocytokines, and measures of adiposity was weak (all rho