Macular Choroidal Thickening in Keratoconus Patients: Swept-Source Optical Coherence Tomography Study.
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- doi: 10.1167/tvst.7.3.15
- issn: 2164-2591
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R. Gutierrez-Bonet et al., « Macular Choroidal Thickening in Keratoconus Patients: Swept-Source Optical Coherence Tomography Study. », Serveur académique Lausannois, ID : 10.1167/tvst.7.3.15
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Résumé
To determine the choroidal thickness (CT) profile in keratoconus (KC) patients using swept-source optical coherence tomography (SS-OCT). This was a prospective, cross-sectional study. One hundred two eyes of 52 KC patients were studied using Pentacam and SS-OCT. The macular CT profile was created by manually measuring the distance between the retinal pigment epithelium and the choroid-sclera junction on horizontal b-scans at nine different macular locations. The results were compared to 93 eyes of 93 healthy controls. Mean age of the KC group was 34.9 ± 13.5 years and mean axial length (AL) was 24.1 ± 1.3 mm. Mean topographic KC classification (TKC) was 2.0; 39 eyes were classified as early KC (TKC 45 years old, losing statistical significance ( P = 0.37). CT in KC patients is statistically thicker than in healthy population. After age 45, CT decreases approaching control group values. This study describes changes in the CT profile of KC patients, a disease that was considered purely corneal. These choroidal changes argue that KC is a disease that likely involves several ocular structures other than the cornea, and could open new research lines related to the pathophysiology of KC.