1 avril 2005
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1186/1471-244X-5-17
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/15804348
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/eissn/1471-244X
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_50A330F58CDE4
info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer
B. Favrat et al., « Two cases of "cannabis acute psychosis" following the administration of oral cannabis. », Serveur académique Lausannois, ID : 10.1186/1471-244X-5-17
Cannabis is the most commonly used illegal drug and its therapeutic aspects have a growing interest. Short-term psychotic reactions have been described but not clearly with synthetic oral THC, especially in occasional users. We report two cases of healthy subjects who were occasional but regular cannabis users without psychiatric history who developed transient psychotic symptoms (depersonalization, paranoid feelings and derealisation) following oral administration of cannabis. In contrast to most other case reports where circumstances and blood concentrations are unknown, the two cases reported here happened under experimental conditions with all subjects negative for cannabis, opiates, amphetamines, cocaine, benzodiazepines and alcohol, and therefore the ingested dose, the time-events of effects on behavior and performance as well as the cannabinoid blood levels were documented. While the oral route of administration achieves only limited blood concentrations, significant psychotic reactions may occur.