Disruption of posteromedial large-scale neural communication predicts recovery from coma.

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Auteurs
Date

2015

Type de document
Périmètre
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Identifiants
Source

Serveur académique Lausannois

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Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1212/WNL.0000000000002196

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/26561296

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/eissn/1526-632X

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_7C0991CD7EF40

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Serveur Académique Lausannois

Organisation

Université de Lausanne et CHUV

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info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer

Mots-clés 0

Adult; Aged; Brain Injuries/diagnosis; Brain Injuries/epidemiology; Coma/diagnosis; Coma/epidemiology; Consciousness/physiology; Female; Glasgow Coma Scale; Gyrus Cinguli/metabolism; Humans; Magnetic Resonance Imaging/methods; Male; Middle Aged; Nerve Net/metabolism; Parietal Lobe/metabolism; Predictive Value of Tests; Recovery of Function/physiology

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Comatose state

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S. Silva et al., « Disruption of posteromedial large-scale neural communication predicts recovery from coma. », Serveur académique Lausannois, ID : 10.1212/WNL.0000000000002196

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OBJECTIVE: We hypothesize that the major consciousness deficit observed in coma is due to the breakdown of long-range neuronal communication supported by precuneus and posterior cingulate cortex (PCC), and that prognosis depends on a specific connectivity pattern in these networks. METHODS: We compared 27 prospectively recruited comatose patients who had severe brain injury (Glasgow Coma Scale score

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