Association of Time of Day When Endovascular Therapy for Stroke Starts and Functional Outcome.

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4 janvier 2021

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info:eu-repo/semantics/altIdentifier/doi/10.1212/WNL.0000000000011449

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info:eu-repo/semantics/altIdentifier/pmid/33397770

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info:eu-repo/semantics/altIdentifier/eissn/1526-632X

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_840213C8D0293

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info:eu-repo/semantics/openAccess , CC BY-NC-ND 4.0 , https://creativecommons.org/licenses/by-nc-nd/4.0/


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S.D. Hajdu et al., « Association of Time of Day When Endovascular Therapy for Stroke Starts and Functional Outcome. », Serveur académique Lausannois, ID : 10.1212/WNL.0000000000011449


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To investigate the association between EVT start time in acute ischemic stroke (AIS) and mid-term functional outcome. This retrospective cohort study included all AIS cases treated with EVT from two stroke center registries from January 2012 to December 2018. The primary outcome was the score on the modified Rankin Scale (mRS) and the utility-weighted mRS (uw-mRS) at 90 days. A proportional odds model was used to calculate the common odds ratio as a measure of the likelihood that the intervention at a given EVT start time would lead to lower scores on the mRS (shift analysis). One thousand five hundred fifty-eight cases were equally allotted into twelve EVT-start-time periods. The primary outcome favored EVT start times in the morning at 08:00-10:20 and 10:20-11:34 (common odds ratio (OR), 0.53; 95% confidence interval (CI), 0.38 to 0.75; P

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