Predicting Ebola Severity: A Clinical Prioritization Score for Ebola Virus Disease.

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info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pntd.0005265

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_A5F4C49BCC072

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M.A. Hartley et al., « Predicting Ebola Severity: A Clinical Prioritization Score for Ebola Virus Disease. », Serveur académique Lausannois, ID : 10.1371/journal.pntd.0005265


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Despite the notoriety of Ebola virus disease (EVD) as one of the world's most deadly infections, EVD has a wide range of outcomes, where asymptomatic infection may be almost as common as fatality. With increasingly sensitive EVD diagnosis, there is a need for more accurate prognostic tools that objectively stratify clinical severity to better allocate limited resources and identify those most in need of intensive treatment. This retrospective cohort study analyses the clinical characteristics of 158 EVD(+) patients at the GOAL-Mathaska Ebola Treatment Centre, Sierra Leone. The prognostic potential of each characteristic was assessed and incorporated into a statistically weighted disease score. The mortality rate among EVD(+) patients was 60.8% and highest in those aged 25 years (p

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