Health-related quality of life in long-term survivors of relapsed childhood acute lymphoblastic leukemia.
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2012
- doi: 10.1371/journal.pone.0038015
- issn: 1932-6203
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S. Essig et al., « Health-related quality of life in long-term survivors of relapsed childhood acute lymphoblastic leukemia. », Serveur académique Lausannois, ID : 10.1371/journal.pone.0038015
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BACKGROUND: Relapses occur in about 20% of children with acute lymphoblastic leukemia (ALL). Approximately one-third of these children can be cured. Their risk for late effects is high because of intensified treatment, but their health-related quality of life (HRQOL) was largely unmeasured. Our aim was to compare HRQOL of ALL survivors with the general population, and of relapsed with non-relapsed ALL survivors. METHODOLOGY/PRINCIPAL FINDINGS: As part of the Swiss Childhood Cancer Survivor Study (SCCSS) we sent a questionnaire to all ALL survivors in Switzerland who had been diagnosed between 1976-2003 at age