Alcoholic liver disease confers a worse prognosis than HCV infection and non-alcoholic fatty liver disease among patients with cirrhosis: An observational study.
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2017
- doi: 10.1371/journal.pone.0186715
- issn: 1932-6203
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_385BD919A2539
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A. Marot et al., « Alcoholic liver disease confers a worse prognosis than HCV infection and non-alcoholic fatty liver disease among patients with cirrhosis: An observational study. », Serveur académique Lausannois, ID : 10.1371/journal.pone.0186715
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Résumé
Cirrhosis is a heterogeneous clinical condition that includes patients at wide-ranging stages of severity. The role of the underlying liver disease on patient prognosis remains unclear. To assess the impact of the underlying liver disease on the occurrence of hepatocellular carcinoma (HCC) and death. Data related to the occurrence of HCC and death were collected during a 21-year period among patients with cirrhosis related to alcoholic liver disease (ALD) (n = 529), chronic hepatitis C virus (HCV) infection (n = 145) or non-alcoholic fatty liver disease (NAFLD) (n = 78). At inclusion, ALD patients were younger than HCV and NAFLD patients (56 vs. 67 vs. 63 years; p