Cancer: Linking Powerhouses to Suicidal Bags.

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Auteurs
Date

2017

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Périmètre
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Source

Serveur académique Lausannois

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Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.3389/fonc.2017.00204

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/28932704

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pissn/2234-943X

Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_030409EABA611

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Serveur Académique Lausannois

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Université de Lausanne et CHUV

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info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer

Mots-clés 0

AMP-activated protein kinase; Rab7; cancer; lysosomal membrane permeabilization; lysosomes; mammalian target of rapamycin; mitochondria; mitophagy

Sujets proches En

Carcinoma Cancers Malignancy (Cancer) Malignant tumors

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L. Martinez-Carreres et al., « Cancer: Linking Powerhouses to Suicidal Bags. », Serveur académique Lausannois, ID : 10.3389/fonc.2017.00204

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Membrane-bound organelles are integrated into cellular networks and work together for a common goal: regulating cell metabolism, cell signaling pathways, cell fate, cellular maintenance, and pathogen defense. Many of these interactions are well established, but little is known about the interplay between mitochondria and lysosomes, and their deregulation in cancer. The present review focuses on the common signaling pathways of both organelles, as well as the processes in which they both physically interact, their changes under pathological conditions, and the impact on targeting those organelles for treating cancer.

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