Meningeal Relapse of Nodular Lymphocyte Predominant Hodgkin Lymphoma Transformed to T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Case Report.
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14 septembre 2020
- doi: 10.3389/fonc.2020.01745
- issn: 2234-943X
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info:eu-repo/semantics/altIdentifier/pmid/33042818
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_F7E269EA64DC9
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Lymphogranuloma Hodgkin disease Pseudoleucemia Lymphosarcoma Hodgkin lymphoma Lymphogranulomatosis Lymphadenoma Hodgkin's lymphomaCiter ce document
P. Salvioni Chiabotti et al., « Meningeal Relapse of Nodular Lymphocyte Predominant Hodgkin Lymphoma Transformed to T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Case Report. », Serveur académique Lausannois, ID : 10.3389/fonc.2020.01745
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Central nervous system involvement in Hodgkin lymphoma is extremely rare, especially in nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), which usually carries a favorable prognosis. Here we report a case of a young patient with NLPHL, who developed a progressive and fatal neurological deterioration requiring a very extensive work-up including two biopsies to obtain the diagnosis of T-cell/histiocyte-rich large B-cell lymphoma like transformation. This report, which includes post-mortem analysis, highlights the correlations between clinical, radiological, and biological data but also the difficulties encountered in reaching the correct diagnosis.