Re-irradiation of recurrent vertebral metastasis after two previous spinal cord irradiation: A case report.

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2022

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Périmètre
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info:eu-repo/semantics/altIdentifier/doi/10.3389/fonc.2022.995376

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info:eu-repo/semantics/altIdentifier/pmid/36698395

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info:eu-repo/semantics/altIdentifier/pissn/2234-943X

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_5064554EC04A8

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info:eu-repo/semantics/openAccess , CC BY 4.0 , https://creativecommons.org/licenses/by/4.0/




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R. Bentahila et al., « Re-irradiation of recurrent vertebral metastasis after two previous spinal cord irradiation: A case report. », Serveur académique Lausannois, ID : 10.3389/fonc.2022.995376


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Management of a recurrent vertebral metastasis in a situation of previously irradiated spinal cord is a challenging clinical dilemma. We report a first case of second retreatment of a spinal metastasis initially irradiated with standard radiotherapy and stereotactic body radiation therapy (SBRT), who subsequently progressed with imaging-confirmed local tumor progression at the same level. After a third course of irradiation with SBRT, a complete response was achieved. After 8 months of follow-up, the patients remain free of local recurrence. A third course of vertebral irradiation for a recurrent vertebral metastasis failing to two previous irradiations, in this particular case, have shown the feasibility and efficacy of the technique as a salvage treatment option. This approach could be used in a selected group of patient if an adequate dose is delivered to the target while observing critical tissue tolerance limits.

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