Neurological Pupil Index for the Early Prediction of Outcome in Severe Acute Brain Injury Patients.

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6 mai 2022

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info:eu-repo/semantics/altIdentifier/doi/10.3390/brainsci12050609

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info:eu-repo/semantics/altIdentifier/pmid/35624996

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info:eu-repo/semantics/altIdentifier/pissn/2076-3425

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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_4475DD6010042

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info:eu-repo/semantics/openAccess , CC BY 4.0 , https://creativecommons.org/licenses/by/4.0/



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F. Romagnosi et al., « Neurological Pupil Index for the Early Prediction of Outcome in Severe Acute Brain Injury Patients. », Serveur académique Lausannois, ID : 10.3390/brainsci12050609


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In this study, we examined the early value of automated quantitative pupillary examination, using the Neurological Pupil index (NPi), to predict the long-term outcome of acute brain injured (ABI) patients. We performed a single-centre retrospective study (October 2016−March 2019) in ABI patients who underwent NPi measurement during the first 3 days following brain insult. We examined the performance of NPi—alone or in combination with other baseline demographic (age) and radiologic (CT midline shift) predictors—to prognosticate unfavourable 6-month outcome (Glasgow Outcome Scale 1−3). A total of 145 severely brain-injured subjects (65 traumatic brain injury, TBI; 80 non-TBI) were studied. At each time point tested, NPi

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