31 juillet 2018
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Stéphane Germain, « Rôle des protéines matricielles dans l’hypoxie et l’angiogenèse / Role of matrix proteins in hypoxia and angiogenesis », Annuaire du Collège de France, ID : 10.4000/annuaire-cdf.13420
Responsable : Stéphane Germain Recherche The sequence of biological events that permits an organism to maintain tissue viability in hypoxia remains poorly understood. Variations in oxygen concentration lead to respiratory, metabolic and vascular adaptations in tissues. How hypoxic endothelial cells (EC) integrate chemical signals with mechanical cues from their local tissue microenvironment in order to produce functional capillary networks that exhibit specialized form remains an open que...